The smfBox is an affordable, modular bench-top single-molecule Microscopy System.

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Single-Molecule Techniques

Modules that are designed to enable researchers to configure their setup and build a portfolio of single-molecule techniques tailored to their research goals.

  • This affordable instrument fits within equipment budgets for standard responsive-mode research grants, making single-molecule techniques accessible to the broader academic community.
  • The cloud-based software enables easy collaboration with options to share your raw and analysed data with specific groups of people or the whole scientific community (for example, upon open-access publication).
  • Online validation of static and dynamic FRET standards ensures optimal instrument operation at all times, alerting users when minor realignment is required / a service visit would be beneficial.
  • A quick and straightforward set up combined with user-friendly acquisition software allows any scientist to obtain their first data rapidly, with no prior experience needed.

Operated by easy‑to‑use software

Democratizing single-molecule techniques : Providing powerful single-molecule applications to researchers at an affordable price.

Single-molecule FRET Applications

Applications: Confocal single-molecule FRET, Fluorescence Correlation Spectroscopy, and TIRF illumination for single-particle tracking and single-molecule localisation microscopy.

Conformational analysis

Identify conformations present in dynamic equilibrium and determine the rates of interconversion between them.

Biomolecular interactions

For example binding constants, especially good for tight binders.

Precise distance determination

For linking FRET data to specific molecular structures by accurately measuring absolute distances.

For more information on our smfBox2 and it's single-molecule FRET applications, get in touch.

Take advantage of this deal just in time to handle the hectic holidays.

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